The clinical effects of triamcinolone acetonide paste and prednisone acetate paste in the treatment of minor aphthous ulcer

VernacularTitle:曲安奈德软膏和泼尼松软膏治疗轻型RAU的疗效观察
Author: Yuefeng SONG ¹ ; Wenmei WANG ; Xiang WANG ; Ning DUAN
Author Information

1. 南京大学医学院附属口腔医院·南京市口腔医院
Keywords: Minor aphthous ulcer; Triamcinolone acetonide paste; Prednisone acetate paste; Short-term effects
From: Journal of Practical Stomatology 2018;34(2):178-181
CountryChina
Language:Chinese
Abstract: Objective: To compare the short-term effects of triamcinolone acetonide paste(TAP) with prednisone acetate paste(PAP) for the treatment of minor aphthous ulcer (miRAU). Methods: 65 patients with miRAU were divided into 2 groups randomly. TAP(n = 32) and PAP(n = 33) were topically applied for the patients in the 2 groups respectively 3 times per day for a week. Ulcer size and pain index(VAS) on day 3 and day 5 were recorded. Re-examination was conducted 1 week after treatment. The effects were compared between the 2 groups. Results: The ulcer size and VAS decreased in the 2 groups after treatment(P＜ 0. 05). In TAP group ulcer size and VAS both decreased more than those in PAP group(P＜ 0. 05). The ulcer duration(d) of TAP and PAP group was 4. 65 ± 1. 91 and 6. 45 ± 1. 09(P＜ 0. 05), the effective rate was 80. 6％ and 34. 5％ (P＜ 0. 05), respectively. Conclusion: Triamcinolone acetonide paste has an advantage in short-term effects over prednisone acetate paste, and it improves the efficiency of treating miRAU.