Comparison of propofol with propofol-remifentanil sedation for third molar extraction
10.3969/j.issn.1001-3733.2018.01.022
- VernacularTitle:靶控输注异丙酚和异丙酚复合瑞芬太尼镇静在第三磨牙拔除术中应用的比较
- Author:
Hao ZHANG
1
;
Yali HOU
;
Fusheng DONG
;
Xiangjun LI
;
Ruihua LIN
Author Information
1. 050017 石家庄,河北医科大学口腔医学院口腔颌面外科,河北省口腔医学重点实验室
- Keywords:
Propofol;
Remifentanil;
Sedation;
Third molar;
Narcotrend index
- From:
Journal of Practical Stomatology
2018;34(1):102-105
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare the sedation induced by target-controlled infusion of propofol with that by propofol-remifentanil in third molar exaction surgery. Methods: 60 patients for third molar exaction were divided randomly into 2 groups(n = 30): group P(propofol group) and group PR(propofol-remifentanil group). In group P,a titrated infusion of propofol was started until the OAA/S score had reached level 3 in the patients,then the surgery began. In group PR,a infusion of remifentanil with a target plasma concentration of 1 ng /ml and a titrated infusion of propofol was started until the OAA/S score had reached level 3,then the surgery began. In all patients,the heart rate,blood pressure,respiratory rate,oxyhemoglobin saturation and narcotrend index were recorded during the operation. The reactions of the patients in the operation were recorded. The satisfaction of the patients and surgeons was asked. Results: The respiratory rate and the oxyhemoglobin saturation in group PR was lower than those in group P(P ＜ 0. 05). No obvious adverse reaction was observed in the 2 groups. The satisfaction of the patients in the 2 groups was 30 /30 and 30 /30(P＞ 0. 05). Conclusion: The sedation induced by target-controlled infusion of propofol or propofol-remifentanil in third molar extraction is safe. The sedation under target-controlled infusion of propofol-remifentanil is better than that by propofol when inhalating oxygen.
