Effectiveness of chlorhexidine gluconate gel dressings combined with chlorhexidine wipe bath on femoral venous central line-associated bloodstream infections in continue renal replacement therapy
10.3760/cma.j.issn.1672-7088.2018.15.015
- VernacularTitle:葡萄糖酸氯己定抗菌敷料联合氯己定擦浴在预防股静脉血滤导管相关血流感染中的效果研究
- Author:
Bo FENG
1
;
Xiulin YE
;
Xingmin XING
;
Yan XU
;
Yuanyuan YAO
;
Yang LI
Author Information
1. 210008,南京大学医学院附属鼓楼医院重症医学科
- Keywords:
Chlorhexidine;
Biological dressings;
Baths;
Hemofiltration;
Catheter-related infections
- From:
Chinese Journal of Practical Nursing
2018;34(15):1182-1185
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevention effect of chlorhexidine gluconate (CHG) gel dressings combined with chlorhexidine wipe bath on femoral venous central line-associated bloodstream infections (CLABSI) in continue renal replacement therapy (CRRT). Methods A total of 593 cases of patients with femoral venous catheter who receipted CRRT were divided into the experimental group and the control group. 282 cases of patients who hospitalized in ICU from January 2016 to December 2016 were assigned into the control group and received 3M transparent dressings and whole-body warm water bathing.Those hospitalized in ICU from January 2017 to November 2017 were assigned into the experimental group including 311cases and received 3M CHG gel dressingscombined with 2％chlorhexidine wipe bathing. Incidence of CLABSI were compared between the two groups. Results 4 cases of patients occurred CLABSI in the experimental group and 12 cases occurred CLABSI in the control group, the difference between groups was statistically significant(χ2=3.900,P<0.05). In the experimental group, 311 cases were retained for 3219 catheter-days, and 282 cases in the control group were retained for 2249 catheter-days. Compared with transparent dressings and whole-body warm water bathing, chlorhexidine gluconate gel decreasescombined with 2％ chlorhexidine wipe bath could reduce the morbidity of CLABSIs from 5.3‰(12/2249) to 1.2‰(4/3219). The on onsite time of CLABSI in the experimental group was (12.5 ± 8.23) days, which in the control group was (10.50 ± 6.46) days, the differenceare not statistically significant (t=0.504,P>0.05). Conclusions CHG gel dressings combined with chlorhexidine wipe bathing would be more effective to prevent CLABSI in CRRT.
