Acute toxicity and cytotoxic effect of Chlorophytum laxum R. Br. (Anthericaceae) \r\n', u'\r\n', u'
- Author:
Hoai Thi Nguyen
;
Ky Thanh Pham
- Publication Type:Journal Article
- Keywords:
Acute toxicity;
cytotoxic effect of Chlorophytum laxum
- MeSH:
Acute toxicity;
cytotoxic effect of Chlorophytum laxum
- From:Journal of Medical and Pharmaceutical Information
2003;0(4):31-34
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Chlorophytum laxum R. Br. (Anthericaceae) are medicinal plants used by people to restore and improve the health of women after birth to boost energy quickly. Objectives: To anounce the results of acute toxicity and cytotoxic effect of Chlorophytum laxum R. Br. (Anthericaceae). Subjects and method: Using an acute toxicity test on Chlorophytum laxum R. Br. (Anthericaceae) collected at Thua Thien Hue province on September, 2005. The data was analysed by bio statistic based on the data analysis of Microsoft Excel. Results:At the dose of 120g/kg body weigh we have not found the oral LD\xac 50 so of the aqueous extract of Chlorophytum laxum R. Br. in mice. Methyl caffeate and 1,2Di-O-(9Z, 12Z- octadecatrienoyl) -3-O-beta-D-galactopyranosylglycerol were isolated from the methanol extract of the roots from Chlorophytum laxum R. Br. have antitumor activity in lung, liver cancer cells and pericardioma. Conclusion: This is the first scientifically published article on the biological effects of Chlorophytum laxum R. Br plant roots, particularly the cytotoxic effects on common cancer cell such as liver cancer, lung cancer from the isolated compounds in pure.
