The clinical efficacy of ultraselective intravascular embolization combined with local sclerotherapy in the treatment of large hemangioma in children
10.3969/j.issn.1002-1671.2018.06.031
- VernacularTitle:超选择血管内栓塞联合局部硬化治疗儿童大型血管瘤的临床疗效
- Author:
Xinxian LIU
1
;
Sui HUANG
;
Fan LIU
Author Information
1. 华中科技大学同济医学院附属武汉儿童医院 武汉市妇幼保健院影像中心
- Keywords:
children;
large hemangioma;
ultraselective endovascular embolization;
local sclerotherapy;
clinical efficacy
- From:
Journal of Practical Radiology
2018;34(6):937-940
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical efficacy and complications of ultraselective endovascular embolization combined with local sclerotherapy in the treatment of large hemangioma in children,to provide a better choice for the treatment.Methods 85 cases of large hemangioma in our department in the last three years were analyzed retrospectively.Patients were divided into two groups according to the treatment:the simple treatment group (33 cases),ultraselective endovascular embolization,and the combination treatment group (52 cases),ultraselective endovascular embolization combined with local sclerotherapy or local sclerotherapy after endovascular embolization.The total effective rate and the incidence of complications between two groups were compared,and the patients were followed up for 3 months to 1.5 years.Results 85 cases of large hemangioma were successfully treated by simple ultraselective endovascular embolization or combined treatment.A total of 75 cases were treated effectively (complete cure,partial cure,condition improved)and 10 cases were ineffective and no recurrence or tumor enlargement in the follow-up .In the total effective rate,the combination treatment group [96.2% (50/52)]was superior to the simple treatment group [75.8% (25/33)](χ2=6.245,P=0.012 ).There was no significant difference in the complete cure rate between the two groups (χ2=1.561,P=0.212 ).The complication rate in the simple treatment group was slightly higher than that in the combined treatment group:36.4% (12/33)vs 32.7% (17/52)(χ2=0.064,P=0.996).Conclusion The total effective rate of ultraselective endovascular embolization combined with local sclerotherapy in the treatment of large hemangioma in children is better than simple endovascular embolization,and less complications,safely treatment and less trauma.It can be used as the first choice for treatment of large hemangioma.
