A quantitative evaluation of lumbar intervertebral disc degeneration by MR T2 * mapping
10.3969/j.issn.1002-1671.2018.05.024
- VernacularTitle:MR T2*mapping定量评价腰椎间盘退变的研究
- Author:
Leitao HUANG
1
;
Yi DING
;
Ning ZHANG
;
Yuan LIU
;
Qi LAI
;
Xia WU
;
Xianjun ZENG
;
Bin ZHANG
;
Min DAI
Author Information
1. 南昌大学第一附属医院骨科(江西省人工关节工程技术研究中心)
- Keywords:
T2 * mapping;
magnetic resonance imaging;
lumbar intervertebral disc;
degeneration
- From:
Journal of Practical Radiology
2018;34(5):740-743,752
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the feasibility and the value of MR T2 * mapping in valuing the early degeneration of lumbar intervertebral disc quantificationally.Methods 67 patients with low back pain and 21 healthy volunteers were chosen for the study.The two groups both underwent 3.0T MR with the axial T2 WI and T2 * mapping images in 440 discs of L1-S1.We graded all intervertebral discs by Pfirrmann score,and measured the T2 * values of annulus fibrosus(AF) and nucleus pulposus(NP).Results The T2 * values of the anterior AF and the NP among different Pfirrmann grades were statistically significant (P =0.001;P =0.000,respectively).There was significant difference in T2 * values of the anterior AF at L3/L4 between patients and volunteers (P=0.043);The T2 * values of the NP at L2/L3,L3/L4,L4/L5,L5/S1 between the two groups were significant difference (P＜0.05).There was also distinct difference in T2 * values of the posterior AF at L1/L2 and L4/L5 between the two groups (P＜0.05).Conclusion The lumbar intervertebral disc degenerates from the NP to posterior AF,and mainly occurs at L4/L5.The T2 * mapping technique can provide a good basis for diagnosing in lumbar intervertebral disc degeneration.
