The value of contrast-enhanced CT and MR DWI in differentiating between autoimmune pancreatitis and pancreatic carcinoma
10.3969/j.issn.1002-1671.2018.05.012
- VernacularTitle:增强CT及MR DWI序列对自身免疫性胰腺炎与胰腺癌的鉴别诊断价值
- Author:
Shuai REN
1
;
Wenjing CUI
;
Jingya CHEN
;
Hui LI
;
Linxiang LIU
;
Zhongqiu WANG
Author Information
1. 南京中医药大学附属医院江苏省中医院放射科
- Keywords:
autoimmune pancreatitis;
pancreatic carcinoma;
computed tomography
- From:
Journal of Practical Radiology
2018;34(5):694-697,701
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of contrast-enhanced CT and MR diffusion-weighted imaging (DWI) in differentiating autoimmune pancreatitis (AIP) from pancreatic carcinoma (PC).Methods Twelve patients with AIP (AIP groups) and 15 patients with PC (PC groups) were included in this study.Contrast-enhanced CT and DWI were performed in all patients.The manifestations of the pancreatic lesions,pancreatic duct and bile duct were observed.The CT attenuation values and the apparent diffusion coefficient (ADC) values of the lesions were calculated.Frequencies of the CT manifestations,and the mean CT attenuation values,and the ADC values were compared between the two groups.Results Most of the AIP showed diffuse enlargement,sausage shape,peripancreatic capsule,penetrating sign of pancreatic duct and thickness of the bile duct.The frequencies of the findings mentioned above were significantly different between AIP and PC (P<0.05).The CT attenuation values of the lesions,and the rate of lesions' CT attenuation values to livers' in 3 phases of contrast enhanced CT were significantly different between AIP and PC (P<0.05).The ADC values of AIP were significantly lower than that of PC (P<0.05).Conclusion The changes of morphology of pancreas,pancreatic and bile duct may facilitate in differentiating AIP from PC.Quantitative analysis of CT attenuation values and ADC values measured on MR images may be helpful in differentiating AIP from PC.