Minimum apparent diffusion coefficient value of DWI in the diagnosis of ductal carcinoma in situ and invasive cancer of breast
10.3969/j.issn.1002-1671.2018.05.010
- VernacularTitle:DWI最小表观扩散系数诊断乳腺导管内癌和浸润性癌的价值
- Author:
Suhong ZHAO
1
;
Weihua GUO
;
Peipei CHEN
;
Liang LI
;
Guangrui SHAO
Author Information
1. 山东大学第二医院影像科
- Keywords:
breast cancer;
invasive ductal carcinoma;
ductal carcinoma in site;
apparent diffusion coefficient
- From:
Journal of Practical Radiology
2018;34(5):686-689
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of the minimum apparent diffusion coefficient (ADC-min) value in the diagnosis of ductal carcinoma in situ (DCIS) and invasive cancer of breast.Methods One hundred and forty nine cases of breast cancer verified by histopathology were included in this retrospective study.All the patients underwent dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted imaging (DWI) before the biopsy.The ADC min value and its correlation with invasive ductal carcinoma(IDC),DCIS and IDC-DCIS were analyzed.Results The mean ADC-min values for IDC,IDC-DCIS and DCIS were (0.95±0.16)×10-3 mm2/s,(1.07±0.13)×10-3 mm2/s and (1.24±0.18)×10-3 mm2/s,respectively.The ADC-min value of the three groups showed an increasing trend and there were significant differences (F=32.08,P＜0.01).The optimal cutoff ADC-min value was 1.02 × 10-3 mm2/s to differentiate DCIS from invasive cancer with a sensitivity of 95.0％ and a specificity of 63.6％.Conclusion The ADC min values are significantly different among IDC,IDC-DCIS and DCIS.It may be used as a reliable tool to differentiate DCIS and invasive cancer of breast.
