The application of MR new technique in primary angiitis of the central nervous system
10.3969/j.issn.1002-1671.2018.05.003
- VernacularTitle:MR新技术在原发性中枢神经系统血管炎诊断中的应用
- Author:
Tianliang SHI
1
;
Ting WANG
;
Xin LOU
;
Lin MA
Author Information
1. 铜仁市人民医院放射科
- Keywords:
primary angiitis of the central nervous system;
arterial spin labeling;
susceptibility weighted imaging;
magnetic resonance spectrum;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2018;34(5):658-661
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study imaging findings of primary angiitis of the central nervous system (PACNS) on MR new techniques,and to explore the diagnostic value of MR new techniques in this disease.Methods Seventeen cases who had been clinically diagnosed as PACNS were enrolled.All the cases underwent MR regular scans [T1 WI,T2 WI,diffusion weighted imaging(DWI),enhanced-enhanced T1 WI] and 3D-posudo-continuous arterial spin labeling (3D-PCASL).Some cases were scanned by using magnetic resonance angiography (MRA),susceptibility weighted imaging (SWI) and magnetic resonance spectrum (MRS) techniques.The regional cerebral blood flow (CBF) values were achieved based on ASL.The inter-group difference of the CBF values were analyzed by independent sample t test.Results Compared to the normal site,the CBF values in the lesion site were significant lower on PACNS (P=0.000).Of 13 patients scanned by SWI,10 cases showed low signal in the lesion.Of 14 patients scanned by MRS,10 cases showed N-acetylaspartic acid (NAA) peak decrease and Cho peak increase and 2 cases showed lactic acid(Lac) peak.Conclusion 3D PCASL can detect the hemodynamic abnormalities of PACNS.SWI can improve the ability of sensibility to observe the microbleed inside the lesion.MRS can explicit the extent of destruction and repairment of neurons in the lesion.Combining with the convention MR images can improve the understanding of the disease and the diagnostic accuracy.
