The study of DCE-MRI quantitative parameters for the pathologic characteristics and clinical stage of cervical cancer at 3.0T
10.3969/j.issn.1002-1671.2018.04.033
- VernacularTitle:3.0T DCE-MRI定量参数对宫颈癌病理学特征及临床分期的研究
- Author:
Zhisen LI
1
;
Jibin ZHANG
;
Jianming XU
;
Ying FEI
;
Yanli LU
;
Mingming QIN
Author Information
1. 南京医科大学附属苏州医院影像科
- Keywords:
cervical cancer;
dynamic contrast-enhanced magnetic resonance imaging;
quantitative parameter
- From:
Journal of Practical Radiology
2018;34(4):609-612
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of 3.0T dynamic contrast-enhanced MRI (DCE-MRI)quantitative parameters for the diagnosis,pathological classification,clinical staging and lymph node status of cervical cancer.Methods The DCE-MRI data of 41 cases with cervical cancer and 1 5 cases with normal cervix were analyzed retrospectively.The quantitative parameters including Ktrans,Kepand Ve were obtained by Siemens Tissue 4D software.Statistical analysis was performed by SPSS 22.0.Results The Ktransand Kepvalues of cervical cancer group were significantly higher than normal cervix group(P<0.001),and there was no statistical difference in Vevalue between the two groups(P>0.05).The Ktransvalue of squamous carcinoma was significantly higher than adenocarcinoma(P<0.05),while Kep and Vevalues showed no statistical differences(P>0.05).The Ktransvalue of International Federation of Gynecology and Obstetrics (FIGO)for early cervical cancer was significantly lower than that for advanced cervical cancer(P<0.05),while Kepand Vevalues showed no statistical differences (P>0.05).There were no statistically significant differences in Ktrans,Kepand Vevalues between cervical cancer with or without lymph node metastasis(P>0.05).Conclusion The quantitative parameters of 3.0T DCE-MRI can be used for the diagnosis, pathological classification and clinical staging of cervical cancer,and it is also of great significance for the rational formulation of the clinical treatment plan.
