The value of multiparametric MRI for predicting prostate cancer extracapsular extension
10.3969/j.issn.1002-1671.2018.04.018
- VernacularTitle:多参数MRI对前列腺癌包膜侵犯的诊断价值
- Author:
Huihui WANG
1
;
Qun HE
;
Qi SHEN
;
Juan HU
;
Ge GAO
;
Xiaoying WANG
Author Information
1. 北京大学第一医院医学影像科
- Keywords:
prostate cancer;
extracapsular extension;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2018;34(4):556-559
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the predictive value of multiparametric MRI (mpMRI)for extracapsular extension (ECE)in patients with prostate cancer.Methods The imaging of prostate mpMRI was performed in 52 consecutive patients with prostate cancer,who underwent subsequent radical prostatectomy.MR images were interpreted retrospectively by one experienced radiologist, who was blinded to any clinical details.According to Prostate Imaging Reporting and Data System Version 2 (PI-RADS v2),suspecious lesions were graded and recorded.Lesions with PI-RADS≥4 were further categorized in terms of ECE and correlated with radical prostatectomy pathology by using side-by-side comparison.Receiver operating characteristic (ROC)curves were used to calculate accuracy,sensitivity,specificity,positive predictive value(PPV)and negative predictive value(NPV),in order to evaluate diagnostic performance of ECE scoring system.Results Totally 55 prostate cancer foci with PI-RADS≥4 were correctly identified by the radiologist.The area under the ROC of ECE score was 0.694 (P=0.013)and ECE score 3 was considered as the best cutoff point with accuracy,sensitivity,specificity,PPV and NPV of 69.3%, 70.4%,67.9%,67.9% and 70.4%,respectively.Conclusion mpMRI is a relatively reliable noninvasive technique for assessment of ECE in clinical practice.
