The application value of liver volume measurement and Gd-EOB-DTPA enhanced MRI to evaluate hepatic reserve function
10.3969/j.issn.1002-1671.2018.04.015
- VernacularTitle:Gd-EOB-DTPA增强MRI与肝脏体积评估肝储备功能的应用价值
- Author:
Xun LI
1
;
Xinguan YANG
;
Yu JIANG
;
Weijia QIU
Author Information
1. 桂林医学院附属医院放射科
- Keywords:
magnetic resonance imaging;
Gd-EOB-DTPA;
liver volume measurement;
hepatic reserve function
- From:
Journal of Practical Radiology
2018;34(4):545-548
- CountryChina
- Language:Chinese
-
Abstract:
Objective To probe the value of both liver volume(LV)measurement and Gd-EOB-DTPA enhanced MRI to evaluate hepatic reserve function in order to obtain a better assessment method.Methods Clinical and imaging data of 42 patients with hepatic focal lesions were analyzed retrospectively.Gd-EOB-DTPA enhanced MRI scan,Child-Pugh scoring and ICG clearance tests were performed in all patients,and the liver relative enhancement (RE)and LV were used to assess the hepatic reserve function.The differences of LV, LV/standard liver volume (SLV)and RE between the Child-Pugh class A and B were compared using independent student's t-test. Spearman correlation analysis was applied to analyze the relationship of indocyanine green retention rate at 1 5 minutes (ICG-R1 5) with the LV,LV/SLV,RE,RE×LV and RE×LV/SLV.Results There was no significant difference in LV between two groups(P>0.05), whereas the RE had significant difference(P=0.039).There were no significant correlations between ICG-R15 and LV,LV/SLV(P>0.05). ICG-R1 5 was negatively correlated with RE,RE×LV and RE×LV/SLV,and RE×LV/SLV showed significant correlation with ICG-R15 (r=-0.524,P=0.000).Conclusion Gd-EOB-DTPA enhanced MRI can assess the status of hepatic reserve function, while the combination of RE with LV is a more effective method.