Preliminary study on quantification of rabbit central nervous system by DTI sequence
10.3969/j.issn.1002-1671.2018.03.034
- VernacularTitle:DTI序列量化兔中枢神经系统的初步研究
- Author:
Chuanyu CUI
1
;
Tianwei WANG
;
Jie LEI
;
Jingbo WU
;
Yanhua CHENG
;
Yuchong WANG
;
Ming YAO
;
Changshuai GENG
;
Rui ZHAO
Author Information
1. 长春市一汽总医院磁共振室
- Keywords:
magnetic resonance imaging;
diffusion tensor imaging;
central nervous system;
rabbit
- From:
Journal of Practical Radiology
2018;34(3):456-458,469
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility and application in quantifying the rabbit central nervous system by using magnetic resonance diffusion tensor imaging(DTI)sequences.Methods 12 normal New Zealand rabbits were used to scan the brain and spinal cord of rabbits by DTI sequence of 1.5T MR machine,and the normal apparent diffusion coefficient(ADC)and fractional anisotropy (FA)values were obtained in the different regions of the brain and every spinal segment of rabbits,to analyse the characteristics and regularity of numerical changes.Results The average ADC value in the brain of rabbits was (0.87±0.08)×10-3mm2/s,the average FA value was 0.23±0.09;the average ADC value in cervical spinal cord was (1.05±0.14)×10-3mm2/s,the average FA value was 0.55±0.08.The average ADC value in thoracic spinal cord was (1.14±0.12)×10-3mm2/s,and the average FA value was 0.57±0.06;the average ADC value in lumber spinal cord was (1.20±0.12)×10-3mm2/s,and the average FA value was 0.61±0.06.Conclusion FA average value in the brain is lower than that in spinal cord (P<0.001),the difference is related to the distribution of nerve fibers and physiological curvature of spine.ADC average value in the brain is lower than that in spinal cord(P<0.001),this is related to the volume of spinal canal and the peripheral structure of spinal cord.The difference of FA value in the brain and spinal cord is higher than ADC value.
