Feasibility of double low techniques in cerebral perfusion using 640-slice volume CT
10.3969/j.issn.1002-1671.2018.03.027
- VernacularTitle:双低技术在640层容积CT脑灌注中的可行性研究
- Author:
Xiaocan WANG
1
;
Fei YANG
;
Yuexiang ZHU
;
Shujun CUI
Author Information
1. 河北北方学院
- Keywords:
cerebral perfusion;
low dose;
image quality;
radiation dose;
contrast medium
- From:
Journal of Practical Radiology
2018;34(3):426-430
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the feasibility of low tube voltage (80 kV)with low concentration contrast medium iodixanol (270 mg I/mL)in cerebral perfusion using 640-slice volume CT.Methods Patients who underwent CT cerebral perfusion were randomly divided into two groups.Group A:100 kV,320 mg I/mL contrast medium;group B:80 kV,270 mg I/mL contrast medium.The effective dose(ED)was record,the frontal cortex,temporal cortex and occipital cortex were selected as regions of interest(ROI),and the cerebral perfusion parameters (rCBV,rCBF,MTT,TTP)were measured separately.The CT value of the M1 segment of cerebral middle artery, the C7 segment of internal carotid artery,the basilar artery and the surrounding brain tissue were measured.The signal-to-noise radio (SNR)and the contrast-to-noise ratio(CNR)of two groups were compared and analyzed.All data will be statistically analyzed,and the consistency of two physicians for image quality evaluation was analyzed by Kappa analysis.Results The ED of group B was 4.56 mSv, which was reduced by 35.2% compared to group A(7.04 mSv).The perfusion parameters,the CT value of ROI and the SNR,CNR for two groups were of no statistical difference(P>0.05).Conclusion The feasibility of low tube voltage combined with low concentration contrast media is better,which not only meets the requirements of clinical diagnosis,but also reduces the radiation dose and the probability of contrast induced nephropathy.
