Total tumor perfusion value of CT in hepatocellular carcinoma with the tumor volume and Child-Pugh classification
10.3969/j.issn.1002-1671.2018.03.013
- VernacularTitle:肝细胞肝癌CT全肿瘤灌注值与瘤体体积、Child-Pugh分级相关性分析
- Author:
Changhua LIANG
1
;
Huajie MAO
;
Junyan YUE
;
Yanlong HU
;
Huijie ZHANG
;
Pan LIANG
;
Jianbo GAO
Author Information
1. 新乡医学院第一附属医院放射科
- Keywords:
hepatocellular carcinoma;
liver reserve function;
Child-Pugh classification;
perfusion imaging;
computed tomography
- From:
Journal of Practical Radiology
2018;34(3):378-381
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between tumor perfusion parameters and tumor volume and Child-Pugh classification in CT of hepatocellular carcinoma (HCC).Methods Fifty-six patients with hepatocellular carcinoma were selected to perform CT perfusion imaging.The parameters of the total tumor perfusion such as hepatic artery perfusion (HAP),portal vein perfusion (PVP)and hepatic perfusion index (HAPI)were calculated according to the degree of hepatic encephalopathy,albumin,bilirubin, clotting time,ascites for liver Child-Pugh classification.The relationship between the tumor or peritumoral perfusion parameters with tumor volume and Child-Pugh classification were analyzed.Results (1)There was no correlation between tumor or peritumoral perfusion with the tumor volume.(2)The difference of HAP,PVP and HAPI between the different Child-Pugh classification groups was statistically significant (P<0.000 1).(3)With the reduction of Child-Pugh classification,the tumor body HAP and HAPI values gradually decreased, while the PVP value increased gradually.Conclusion There is no correlation between the tumor volume of hepatocellular carcinoma with total tumor perfusion parameters.The differences in perfusion measurements between different Child-Pugh classification can intuitively and quantitatively reflect the reserve function of the liver.
