Application of cMRI and MRS in diagnosis and differential diagnosis of single brain metastases and localized high grade gliomas
10.3969/j.issn.1002-1671.2018.03.006
- VernacularTitle:cMRI与MRS在单发脑转移瘤与局限性高级别胶质瘤的诊断及鉴别诊断中的应用
- Author:
Shenghai WANG
1
;
Lu WANG
;
Peiling LI
;
Zhengrong BAI
;
Zhenxian ZHANG
;
Yanling YANG
Author Information
1. 延安市人民医院CT诊断科
- Keywords:
metastatic tumor;
high grade glioma;
conventional magnetic resonance imaging;
magnetic resonance spectrum
- From:
Journal of Practical Radiology
2018;34(3):351-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of cMRI and MRS in diagnosis and differential diagnosis of single brain metastases and localized high grade gliomas.Methods The cMRI (T1WI,T2WI and contrast-enhanced MRI)and MRS data of 23 cases with single brain metastases and in 28 cases with high grade gliomas confirmed by pathology were collected and analyzed retrospectively.Results cMRI:①There were no significant differences of T1WI,T2WI and constrast-enhanced MRI between single brain metastases and high-grade gliomas.②Enhanced images of single brain metastases and localized high-grade gliomas showed that there was a significant difference in the peritumoral edema area:the nodular or ring enhancement were found in single brain metastases,the outer outline of ring enhancement was smooth,and there was no enhancement at the peripheral edema area;Irregular patchy or ring enhancement were found in localized high-grade glioma tumor,both of the outer and inner edges of the ring enhancement rough,a little patchy enhancement at the peripheral edema area were found in 1 6 patients,and there was no enhancement of the edema area in the other 1 2 patients.MRS:①There were no significant differences of the tumor parenchyma in the peaks of NAA,Cr,Cho and central Lac between single brain metastases and localized high grade gliomas.②A significant difference of the peripheral edema area were observed between them.The peaks of NAA,Cr,Cho at the edema area in all single brain metastases patients were normal.But in all high-grade glioma patients,the NAA and Cr peaks were decreased,while the Cho peaks were increased.Conclusion The morphological manifestations of single brain metastases are similar to localized high grade gliomas.An obvious difference of cMRI and MRS lines exists in the peritumoral edema area between them,which could be used for differential diagnosis.
