Semi-quantitative analysis of hepatic fat in MR using Dixon technique and its clinical significance
10.3969/j.issn.1002-1671.2018.02.033
- VernacularTitle:基于MR Dixon技术的肝脏脂肪半定量分析及其临床意义
- Author:
Yong LIU
1
;
Ben SHAN
;
Hansong ZHOU
;
Dongyang YU
;
Hao DONG
;
Chunhong HU
Author Information
1. 苏州大学附属第一医院放射科
- Keywords:
non-alcoholic fatty liver disease;
fat fraction;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2018;34(2):291-295
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between hepatic fat fraction(HFF)and some clinical indicators by measuring HFF and summarize its clinical significance.Methods A total of 95 patients were included in this study.MR data were acquired with Dixon technique,and the HFF of liver were measured.According to the HFF,all patients were divided into high-fat group and low-fat group.Subcutaneous fat area(SA),visceral fat area(VA)and total fat area(TA)were also measured.The age of patients,blood pressure, fasting blood glucose(FPG),total cholesterol (TC),triglyceride (TG),low density cholesterol (LDL-c)and high density cholesterol (HDL-c) were recorded and the body mass index(BMI)was calculated.Results The levels of FPG,TG,LDL-c,systolic blood pressure,diastolic blood pressure,BMI,VA,TA and visceral fat percentage (VFP)in high-fat group were significantly higher than those in low-fat group (P<0.05), while the abdominal subcutaneous fat percentage (SFP)was significantly lower than that in low-fat group (P<0.05).HFF was positively correlated with FPG,TG,LDL-c,VA,TA,VFP,age and BMI (r=0.354,0.370,0.415,0.299,0.285,0.238,0.203,0.221,respectively;P<0.05).Conclusion Semi-quantitative analysis of hepatic fat using MR Dixon technique can reflect the degree of hepatic fatty infiltration, and can be used as a quantitative indicator for early diagnosis and treatment evaluation of nonalcoholic fatty liver disease.
