Regional homogeneity alterations of brain in patients with idiopathic trigeminal neuralgia:a rs-fMRI study
10.3969/j.issn.1002-1671.2018.02.001
- VernacularTitle:特发性三叉神经痛患者局部一致性的rs-fMRI研究
- Author:
Wei XIE
1
;
Zongfang LI
;
Wei ZHAO
;
Zhenguang ZHANG
;
Yuanming JIANG
;
Qing WANG
;
Huimei ZHANG
Author Information
1. 昆明医科大学第一附属医院医学影像中心
- Keywords:
idiopathic trigeminal neuralgia;
resting-state functional magnetic resonance imaging;
regional homogeneity
- From:
Journal of Practical Radiology
2018;34(2):167-170
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of the regional homogeneity(ReHo)values of spontaneous brain activity in patients with idiopathic trigeminal neuralgia (ITN).Methods Left ITN (LITN)group (n=23)and the healthy control (HC)group (n=33)underwent resting-state functional magnetic resonance imaging(rs-fMRI)scans.The changes of ReHo values between the two groups were compared.Results Compared with HC group,LITN group yielded increased ReHo values in bilateral nucleus accumbens,bilateral caudate nucleus,right putamen, right precentral gyrus (M1),right supplementary motor area (SMA)and right anterior insula (P<0.01).Conclusion The rs-fMRI shows abnormal ReHo values of brain activity in several regions in ITN patients.The regions are related to pain processing-motion,emotion and endogenous regulation.The suggest that brain involves the developing and regulating mechanism of ITN as an importment factor.
