Clinical efficacy of improved TIPS therapy in portal hypertension with acute upper gastrointestinal bleeding
10.3969/j.issn.1002-1671.2018.01.027
- VernacularTitle:改良TIPS治疗门静脉高压急性上消化道出血疗效观察
- Author:
Wenjun HU
1
;
Nan ZHENG
;
Penggang CAO
;
Youzhi WANG
;
Yeyu XIAO
Author Information
1. 东莞市第五人民医院介入科
- Keywords:
percutaneous portal vein puncture;
TIPS;
cirrhosis;
esophageal varices;
bleeding
- From:
Journal of Practical Radiology
2018;34(1):98-100,125
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical efficacy of improved TIPS of percutaneous portal vein puncture in treatment of acute upper gastrointestinal bleeding induced by portal hypertension.Methods 28 patients with acute upper gastrointestinal bleeding underwent improved TIPS therapy in our hospital were enrolled.The clinical data,laboratory parameters and hemodynamic changes were collected and analyzed before and after operation.Results The success rate for the first time and hemostatic rate of postoperative 24 hours in all patients was 100%.2(7.14%)patients underwent mild hepatic encephalopathy.After TIPS operation,the concentration of serum albumin increased,whereas,concentration of total bilirubin and alanine aminotransferase decreased(P<0.01).Portal vein pressure (PVP)of pre-and post-operation was(41.48 ± 3.72)mmHg and(28.91 ± 2.59)mmHg,and the hepatic venous pressure gradient (HVPG)was(20.30 ± 2.76)mmHg and(8.81 ± 2.04)mmHg.PVP and HVPG were both decreased significantly after operation(P<0.01).Conclusion Improved TIPS therapy can obtain good clinical efficacy and safety for esophageal and gastric varicose bleeding in acute cirrhosis.
