A Case of Melanotrichoblastoma.
- Author:
Hyun Soo SHIM
1
;
Jong Won SEO
;
Jong Keun SEO
;
Sook Kyung LEE
Author Information
1. Department of Dermatology, Maryknoll Medical Center, Busan, Korea. sooya107@hanmail.net
- Publication Type:Case Report
- Keywords:
Melanotrichoblastoma;
Trichoblastoma
- MeSH:
Female;
Hair;
Humans;
Immunohistochemistry;
Melanins;
Melanocytes;
Monophenol Monooxygenase;
Virtues
- From:Korean Journal of Dermatology
2009;47(1):80-83
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Melanotrichoblastoma is a variant of pigmented trichoblastoma that shows highly pigmented epithelial lobules and differentiation toward the hair bulb. Histologically, the tumor presents features of trichoblastoma, and the histological findings are remarkable by virtue of the heavy melanin deposits found within and around the tumor cell nests. For the immunohistochemistry, abundant dendritic melanocytes (with the expressions of S100 protein, tyrosinase and most importantly, gp100/HMB45) are found within the tumor masses. We report here on a rare case of melanotrichoblastoma in a 57 year-old female patient.