Vitamin D metabolism and rheumatic autoimmune diseases
10.3760/cma.j.issn.2095-428X.2018.21.018
- VernacularTitle:维生素D代谢与风湿免疫性疾病的研究进展
- Author:
Wenlin WU
1
;
Yiru ZENG
;
Huasong ZENG
Author Information
1. 510623,广州市妇女儿童医疗中心儿内科
- Keywords:
Vitamin D;
1,25 (OH) 2 D;
Metabolism;
Rheumatoid arthritis;
System lupus erythematosus
- From:
Chinese Journal of Applied Clinical Pediatrics
2018;33(21):1673-1676
- CountryChina
- Language:Chinese
-
Abstract:
1,25 (OH)2D,the active form of vitamin D,plays several roles in the body,influencing bone health as well as serum calcium and phosphate levels.Further,1,25(OH) 2D plays an important role in modifying immune function including improving innate immunity and suppressing autoimmune diseases by regulating adaptive immunity.For now,there is already some understanding of the links between 1,25 (OH)2D and rheumatic autoimmune diseases like rheumatoid arthritis and system lupus erythematosus and its regulatory mechanisms involved in these diseases.However,supplement vitamin D in these patients is still in the exploratory stage.The purpose of this article is to summary the recent advances in the links between the metabolism of vitamin D and rheumatic autoimmune diseases.
