Liver stiffness and hepatic steatosis measurement of preschool children in Shanghai by using transient elasto-graphy
10.3760/cma.j.issn.2095-428X.2018.19.008
- VernacularTitle:瞬时弹性成像用于上海学龄前体检儿童肝脏硬度及脂肪定量检测研究
- Author:
Jing ZENG
1
;
Lisu HUANG
;
Qin PAN
;
Jiangao FAN
Author Information
1. 脂肪肝诊疗中心
- Keywords:
Transient elastography;
M - probe;
Child;
Liver stiffness;
Hepatic steatosis
- From:
Chinese Journal of Applied Clinical Pediatrics
2018;33(19):1483-1485
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of transient elastography (TE)by using transient elas-tography(FibroScan)for the noninvasive diagnosis of hepatic fibrosis and steatosis by measuring liver stiffness (LS)and controlled attenuation parameter (CAP)in the preschool children in Shanghai for their health check - up. Methods A total of 410 children,who underwent health screening in Xinhua Hospital,Affiliated to Shanghai Jiaotong University School of Medicine,from April to November 2017 were collected. LS and CAP values were obtained by the FibroScan device with M - probe. The differences in LS and CAP values between different genders were analyzed,as well as the in-fluencing factors for LS and CAP values. Results A total of 410 preschool healthy children were enrolled. The success rate of valid TE measurements by M - probe in the participating children was 96. 5％ . The LS and CAP values were (3. 22 ± 0. 86)kPa and (176. 74 ± 20. 84)dB/ m,respectively. LS and CAP values didn′t differ significantly in gender (all P > 0. 05). In univariate analysis,the CAP values were significantly associated with height (r = 0. 112,P =0. 026),weight(r = 0. 145,P = 0. 004),body mass index(r = 0. 114,P = 0. 023),waist circumference(r = 0. 178,P =0. 000)and hip circumference(r = 0. 148,P = 0. 003). Conclusions FibroScan equipped with M - probe is feasible for LS and hepatic steatosis measurement in preschool children.
