Risk factors for heart failure in children with Mycoplasma pneumoniae infection
10.3760/cma.j.issn.2095-428X.2018.18.011
- VernacularTitle:儿童肺炎支原体感染并心力衰竭的高危因素
- Author:
Chengyi WANG
1
,
2
;
Shibiao WANG
;
Ling WU
;
Qin CHEN
Author Information
1. 350001福州,福建省妇幼保健院,福建医科大学附属医院儿科
2. 361024厦门,福建省医疗数据挖掘与应用工程技术研究中心
- Keywords:
Mycoplasma pneumoniae;
Clinical characteristics;
Child;
Heart failure;
Risk factor
- From:
Chinese Journal of Applied Clinical Pediatrics
2018;33(18):1411-1414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the high risk factors for children with Mycoplasma pneumonia infection complicated with heart failure.Methods Retrospective analysis was utilized to analyze the clinical data of the 33 children who were hospitalized at Pediatric Intensive Care Unit of Fujian Provincial Maternity and Children's Hospital due to Mycoplasma pneumonia infection complicated with heart failure between January 2014 and October 2017 (the case group),male 15,female 18,aged from 3 month to 8 years old.A total of 66 concurrent children with Mycoplasma pneumonia infection without complications were selected as a control group,male 32,female 34,aged from 1 month to 8 years old.The overall data and laboratory findings in the case group and the control group were compared,and high risk factors for heart failure in children with Mycoplasma pneumoniae infection were analyzed by multivariate Logistic regression analysis.Results (1)There was no significant difference in gender,age,duration of fever,white blood cell,platelet count,the proportions of cough,fever,pulmonary rales,large shadow of lung,abnormal electrocardiographic pattern between 2 groups (all P ＞ 0.05).(2) Compared to the control group,the children with Mycoplasma pneumonia infection complicated with heart failure were more prone to longer time intervals from the onset to the application of macrolide drugs (5.27 d vs.4.09 d),lower hemoglobin and prealbumin,higher C-reactive protein,lactate dehydrogenase and MB isoenzyme of creatine kinase (CK-MB)(all P ＜ 0.05),there were significant differences in the proportions of co-infection of 2 or more noxae between 2 groups (45.5 ％ vs.18.1％,x2 =8.250,P =0.004).(3) Logistic regression multifactor analysis showed hemoglobin(OR =0.875,95％ CI:0.793-0.965,Wald x2 =7.167,P ＜ 0.01),prealbumin (OR =0.567,95％ CI:0.372-0.863,Wald x2 =6.998,P ＜ 0.01),lactate dehydrogenase (OR =1.030,95％ CI:1.010-1.051,Waldx2 =8.651,P ＜0.01) were associated with children with mycoplasma pneumonia infection complicated with heart failure.Conclusion Hemoglobin,prealbumin and lactate dehydrogenase are risk factors related to Mycoplasma pneumonia infection complicated with heart failure.
