Protracted bacterial bronchitis and primary ciliary dyskinesia in children
10.3760/cma.j.issn.2095-428X.2018.10.006
- VernacularTitle:儿童迁延性细菌性支气管炎与原发性纤毛运动障碍
- Author:
Baoping XU
1
;
Hao WANG
Author Information
1. 100045北京,国家儿童医学中心,首都医科大学附属北京儿童医院呼吸科,国家呼吸系统疾病临床
- Keywords:
Protracted bacterial bronchitis;
Primary ciliary dyskinesia;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2018;33(10):735-739
- CountryChina
- Language:Chinese
-
Abstract:
Protracted bacterial bronchitis (PBB) and primary ciliary dyskinesia (PCD) have the same pathogenetic change of abnormal mucociliary clearance,but the initial factors are different.The former is the secondary changes caused by infections,and the latter is caused by ciliary structure and/or dysfunction.They all have chronic wet cough,so the differential diagnosis is important.Visceral transposition,recurrent otitis media,sinusitis and pseudomonas aeruginosa infection can help to identify PCD from PBB.But if the patients have recurrent PBB or no reaction to common antibiotic therapy,PCD is needed to be identified.Rational application of antibacterial drugs and whole course vaccine inoculation to prevent recurrent infections are important to both of the two diseases.