Advances in the application of biological agents in juvenile idiopathic arthritis
10.3760/cma.j.issn.2095-428X.2018.09.002
- VernacularTitle:幼年特发性关节炎生物制剂临床应用进展
- Author:
Yajun WANG
1
;
Jian WAN
Author Information
1. 云南省第一人民医院儿科
- Keywords:
Juvenile idiopathic arthritis;
Biological agents;
Treatment
- From:
Chinese Journal of Applied Clinical Pediatrics
2018;33(9):646-650
- CountryChina
- Language:Chinese
-
Abstract:
Juvenile idiopathic arthritis (JIA)is a type of chronic rheumatism in children. It is mainly charac-terized by joint damage,accompanied by systemic symptoms and result in significant morbidity. The application of bio-logical agents has altered the traditional treatment pattern of JIA and significantly improved the condition of JIA pa-tients. JIA is a heterogeneous disease. Treatment recommendations issued by American College of Rheumatology(ACR) in 2011 have become an important reference for JIA treatment. There is a best response window for JIA treatment. Thus, the clinic application of biological agents should be used as soon as possible after the diagnosis of JIA. Meantime,it should be noted when a preparation is invalid,it need to use another possible biological agent in time to control disease progression.
