Recent advance in epidemiology of enterovirus 71 and pathogenesis of central nervous system damage induced by enterovirus 71 infection
10.3760/cma.j.issn.2095-428X.2017.22.022
- VernacularTitle:肠道病毒71型流行病学及其感染致中枢神经系统损伤的研究进展
- Author:
Bangtao LI
1
;
Hongai LI
;
Lan CUI
;
Yuanping HAI
;
Ting HUANG
;
Wei XIANG
Author Information
1. 海南省妇幼保健院(海南省儿童医院)重症医学科
- Keywords:
Enterovirus 71;
Epidemiology;
Central nervous system;
Pathogenesis
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(22):1754-1756
- CountryChina
- Language:Chinese
-
Abstract:
Enterovirus 71 (EV71) has a high degree of nerve absorption and which is an important neurotoxic pathogen causing severe hand,foot and mouth disease and central nervous system(CNS) diseases.EV71 infection is at a high incidence in Asia Pacific region.The CNS damage caused by EV71 mainly includes aseptic meningitis,encephalitis,brain stem encephalitis,acute flaccid paralysis,etc,which has a high mortality and poor prognosis,while its injury mechanism is not clear.Now,EV71 related etiology,epidemiology,pathogenesis of CNS damage caused by EV71 infection and EV71 vaccine research progress were summarized,in order to provide theoretical basis for EV71 related studies.
