Analysis of the Influence of Different MCV Level on the Platelet False Increase Counts
10.3969/j.issn.1671-7414.2018.02.030
- VernacularTitle:低MCV引起PLT计数假性增高的实验研究
- Author:
Jing JING
1
;
En-Liang HU
;
Ai-Lin FAN
;
Shan-Luan ZHENG
;
Xiao-Ke HAO
Author Information
1. 空军军医大学西京医院检验科
- Keywords:
PLT count;
small red blood cell;
blood cell debris;
MCV
- From:
Journal of Modern Laboratory Medicine
2018;33(2):108-110
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the influence of the mean corpuscular volume (MCV) in different ranges on PLT counts,provide the theoretical basis for making PLT counts review rules in laboratory.Methods From March 2016 to August 2016 in Xijing Hospital department of outpatient who perform complete blood cell count were randomly divided into 3 groups,MCV≤65 fl in A group,65 fl<MCV≤70 fl in B group and 70 fl<MCV≤75 fl in C group.The reference method (Coulter principle) compared with the fluorescence method,accuracy analysis of different monitoring methods of counting PLT.Results PLT I and PLT F count values in A group was (322.8± 109.1) × 109/L and (282.60± 100.5) × 109/L respectively,and there was significant differences between the two groups (t=6.799,P<0.05).In B group,the count values was (305.7 ± 111.7)× 109/L and (304.8 ± 112.3)× 109/L respectively,and there was no differences between two groups.In C group,the count values was (292.2±84.4) × 109/L and (291.6±84.4) × 109/L respectively,and there was no differcnces between two groups neither.Conclusion When small red blood cells or blood cell debris present in blood circulation,MCV≤65 fl,the reference testing (Coulter principle)of platelets causes a false increase in platelet count.