Clinical Significance of the Ratio of Neutrophil to Lymphocyte in the Differential Diagnosis of Primary Ulcerative Colitis and the Judgment of Its Severity
10.3969/j.issn.1671-7414.2018.01.038
- VernacularTitle:中性粒细胞与淋巴细胞比值对初发溃疡性结肠炎鉴别诊断及其严重程度判断的临床意义
- Author:
Zheng-Yu ZHOU
1
;
Qian GAO
;
Li-Ling JING
;
Zhan-Yi YUE
;
Jie MENG
;
Shan-Rong LIU
Author Information
1. 海军军医大学附属上海长海医院实验诊断科
- Keywords:
neutrophil to lymphocyte ratio;
ulcerative colitis(UC);
irritable bowel syndrome(IBS)
- From:
Journal of Modern Laboratory Medicine
2018;33(1):145-147,150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical impact of neutrophil to lymphocyte ratio (NLR) in the diagnosis of ulcerative colitis.Methods The study included 97 patients with ulcerative colitis (UC) and 95 patients with irritable bowel syndrome (IBS) from June 2009 to June 2016.The differences of NLR between the two groups were analyzed and the result of sensitivity and specificity were calculated.The differencesn of NLR were analyzed between the groups of different severity and in different lesionsseparately.Results NLR were significantly higher in ulcerative colitis than in irritable bowel syndrome (t=2.327,P＜0.021).Sensitivity was 69.1 ％ and specificity was 75.8 ％.There was statistic different in groups of different severity determination of newly diagnosed ulcerative colitis (F=8.221,P=0.001)and there was no statistic different between different lesions (F=0.737,P=0.483).Conclusion NLR is valuable in the diagnosis of UC and IBS can determine the degree of inflammation of ulcerative colitis.
