Research Progress of PK / PD in Chemical Constituents of Traditional Chinese Medicine
10.11842/wst.2017.11.019
- VernacularTitle:中药化学成分PK/PD研究进展
- Author:
Linjin LIANG
1
;
Lingfang WU
;
Ting YE
;
Qi QI
;
Yaping CUI
;
Shi LI
;
Wenyi LIANG
;
Wenjing CHEN
;
Lanzhen ZHANG
Author Information
1. 北京中医药大学中药学院 北京 100102
- Keywords:
Traditional Chinese medicine;
chemical constituents;
PK-PD;
research progress
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(11):1872-1877
- CountryChina
- Language:Chinese
-
Abstract:
PK-PD binding model is a powerful tool to study the relationship between drug time-concentration,concentration-effect and time-effect,which is of great significance and widely used in guiding clinical medicine.The PK-PD binding model is applied to the study of traditional Chinese medicine (TCM),which is helpful to elucidate the basis of drug substance and its mechanism.It is of great significance to the development of TCM and its preparation.In this paper,recent applications of PK-PD binding model in the composition and effective part of TCM,single herbal medicine and TCM compound were made,which could provide references for future PK-PD study of chemical constituent.
