Research on Antibacterial, Anti-inflammatory and Antitussive Effects of Water Extract of Styrax japonicus Leaves
- VernacularTitle:野茉莉叶水提物抑菌、抗炎及止咳作用的实验研究
- Author:
Jie REN
1
,
2
;
Juan LI
;
Zhaoxing LI
;
Mingdan LI
;
Hongliang ZENG
;
Shanqing PAN
;
Rixing LI
;
Shunxiang LI
Author Information
- Keywords: Styrax japonicus leaves; antibacterial; anti-inflammatory; antitussive
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(11):1851-1855
- CountryChina
- Language:Chinese
- Abstract: This study was aimed to explore the in vitro antibacterial,anti-inflammatory and antitussive effects of water extract of Styrax japonicus leaves and to verify its concerning efficacies.In vitro antibacterial,anti-inflammatory and antitussive effects were observed by in vitro antibacterial experiment,cotton ball implantation,carrageenan-induced paw edema together with xylene-induced ear edema experiments with rats or mice,and ammonia hydroxide-induced coughing experiment,respectively.The results showed that water extract of Styraxjaponicus leaves can inhibit the growth of Escherichia coli,Klebsiella pneumoniae,Salmonella and Staphylococcus aureus except candida albicans.Its high-dose group can reduce the weight of cotton ball granuloma in rats obviously.And its low-dose and high-dose groups can inhibit carrageenan-induced paw edema apparently.Meanwhile,its low-dose and high-dose groups can improve xylene-induced ear edema distinctively.Its low-dose and high-dose groups can evidently prolong the ammonia hydroxide-induced coughing incubation periods.And all groups can reduce coughing times.It was concluded that the water extract of Styrax japonicus leaves coincided with the relative clinical efficacy of traditional Chinese medicine (TCM) and provided experimental evidences for its clinical application to some degree.
