Research on Characteristics of Compound Kushen Injection in The Treatment of Patients with Malignant Lymphoma: A Real-world Study
- VernacularTitle:复方苦参注射液治疗淋巴恶性肿瘤真实世界临床用药人群特征研究
- Author:
Pan WANG
1
,
2
;
Yanming XIE
;
Yin ZHANG
;
Cen CHEN
;
Yan ZHUANG
;
Zhiwei JIN
Author Information
- Keywords: Malignant lymphoma; Compound Kushen injection; real-world study; hospital information system; electronic medical record
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(10):1718-1723
- CountryChina
- Language:Chinese
- Abstract: This study was aimed to analyze the clinical characteristics of Compound Kushen Injection in the treatment of patients with malignant lymphoma in the real world based on the electronic medical record,and to provide a reference for its rational application.The electronic medical data of 3 674 patients with malignant lymphoma using Compound Kushen Injection was extracted.General information,diagnostic information,and medication information were analyzed on the basis of frequency and rate of descriptive analysis.The results showed that the average age of patients was 54.95 yearsold,with more males than females.Patients were mainly from the department of oncology and hematology.Based on hospital outcomes in hospitalized patients,the clinical total effective rate was 66.15％.The single medication dosage was mostly 10-20 ml.The course of treatment was mainly 4-14 days.The common western medications in combination included dexamethasone,tropisetron injection,metoclopramide tablet,thymopolypeptides injection,cyclophosphamide injection,and etc.Common pharmacological effects of combined western medicine included anti-tumor chemotherapy drugs,immunomodulatory drugs,glucocorticoid drugs,antibiotic drugs and so on.It was concluded that the clinical dosage,scope of malignant lymphoma treatment using Compound Kushen Injection in the real world were consistent with the specification.And characteristics of the crowd using Compound Kushen injection is clear and in line with the general rule of malignant lymphoma and clinical positioning of varieties.Based on the hospital outcomes,the clinical efficacy is determined to have precise effect on hospitalized patients.The drug combination type is extensive.
