Clinical Study of Wen-Yang Jian-Pi Decoction in Treatment of Hepatitis B Cirrhosis Patients with Refractory Ascites
10.11842/wst.2017.10.013
- VernacularTitle:温阳健脾汤加减治疗乙肝肝硬化顽固性腹水临床研究
- Author:
Jian ZHANG
1
;
Haiping LIU
;
Jijun TANG
Author Information
1. 菏泽市中医医院 菏泽274000
- Keywords:
Hepatitis B cirrhosis;
refractory ascites;
diuretic-resistant ascites;
spleen-kidney yang deficiency;
Wen-Yang Jian-Pi decoction;
clinical study
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(10):1666-1670
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to observe the clinical curative effect of Wen-Yang Jian-Pi (WYJP) decoction for treating hepatitis B cirrhosis patients with refractory ascites.A total of 81 hepatitis B cirrhosis patients with refractory ascites after admission to our hospital were randomly divided into two groups,41 patients were in the treatment group and 40 were in the control group.Patients in both groups received basic treatment,including antivirus,liver-protective,antiinfective and diuretic therapy,as well as albumin supplementation;while the treatment group were additionally given oral traditional Chinese medicine (TCM) of WYJP decoction at the same time.Changes of subjective symptoms,abdominal circumference,urine volume,main hepatic function indexes,and main indexes of B-ultrasound before and after treatment were measured and compared between two groups.Patients in both groups were treated for 3 one-month therapeutic courses,with 3 to 5 day-intervals,after which the curative effect was evaluated.The results showed that the total effective rate in the treatment group was 87.8％,which was significant higher than that of 70.0％ in the control group (P ＜ 0.05).And the treatment group in ascites,urine volume,symptoms,body signs and B ultrasonic improvement were better than those of the control group,with statistical significance (P ＜ 0.05).It was concluded that WYJP decoction has definite therapeutic effect on hepatitis B cirrhosis patients with refractory ascites.
