The Study and Regulation of Active Ingredients Has Broad Application Prospect in the Production of Chinese Herbal Medicine
- VernacularTitle:有效成分生源途径解析与调控技术在中药材生产实践中具有广阔应用前景
- Author:
Lei ZHANG
1
;
Junfeng CHEN
;
Ying XIAO
;
Hexin TAN
;
Qing LI
;
Wansheng CHEN
Author Information
- Keywords: Traditional Chinese medicine quality; Active ingredients; Biosynthesis pathway; Genetic mechanisms; Molecular markers; Quality control
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(10):1623-1628
- CountryChina
- Language:Chinese
- Abstract: The resources and quality of Chinese herbal medicine is the foundation and guarantee for the sustainable development of the whole industry chain of traditional Chinese medicine.The effective component,having clinical curative effect,is the material base of Chinese herbal medicine,and is the core for the quality of medicinal material factors (quality).The accumulation of efficacy material is closely related to the genetic background of the original plant.By clarifying active ingredients biosynthesis,revealing medicinal material quality formation mechanism,regulating the content of effective components,the quality of medicine could be guarantee and ascend.The quality control technology based on active ingredients of Traditional Chinese medicine quality includes integrated analysis of high-throughput sequencing and systems biology data,revealing synthetic genetic mechanisms of active ingredients,excavating molecular markers of the quality,creating excellent germplasm,forming cultivation techniques,establishing classification standard of medicinal materials,and finally realizes the full industrial chain control of Chinese herbal medicine production.Taken all of these together could ensure the quality of medicinal materials.
