Fuzhengkangai Particle Combination HAART Therapy in Patients with HIV/AIDS Clinical Curative Effect and Adverse Reactions of Clinical Research
- VernacularTitle:扶正抗艾颗粒联合HAART疗法对HIV/AIDS患者临床疗效和不良反应的临床研究
- Author:
Jianzhong LIU
1
,
2
;
Yao CHEN
;
Mingzhong XIAO
;
Wei NI
;
Shengyong WANG
;
Xingqing QIU
;
Hongchun LIAO
;
Zhen TAN
;
Hongying CHEN
;
Duan WU
;
Lei TANG
Author Information
- Keywords: Fuzhengkangai particle; HAART therapy; HIV/AIDS; Clinical curative effect; Adverse reactions
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(8):1360-1364
- CountryChina
- Language:Chinese
- Abstract: Objective:to apply Fuzhengkangai AIDS particles combined therapy with effective antiretroviral therapy (HAART) at the beginning of the HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome) patients,observe its clinical curative effect and improve the related adverse reactions.Methods:a multicenter,randomized,double-blind,placebo-controlled clinical research method,divided into experimental group and the control group (n =57),experimental group to "Fuzhengkangai particles" joint efficient antiretroviral therapy (HAART) antiviral treatment,control group to "Fuzhengkangai particles" placebo (5％ low dose) joint efficient antiretroviral therapy (HAART) antiviral treatment,treatment for 3 months.Two groups of patients with simultaneous liver and kidney function,blood routine,CD4 + T lymphocyte count,the observation of TCM symptoms and signs,survival quality of integral.Results:after 12 weeks of treatment,the control group and experimental group,the experimental group significantly elevated levels of peripheral blood RBC,lower levels of CR,reduce the signs and symptoms (total score,fatigue,stay,and spontaneous perspiration)integral,higher levels of CD4 + T lymphocyte count and survival quality score,the difference had statistical significance (p ＜ 0.05).Conclusion:Fuzhengkangai particles joint efficient antiretroviral therapy (HAART) antiviral treatment,can improve HAART after initial treatment of the patient's clinical symptoms,blood toxicity,the quality of survival,reduce the antiviral treatment of adverse reactions,combination drug alone can significantly increase the CD4 + T lymphocytes,so as to improve clinical curative effect.
