- VernacularTitle:血管性抑郁症功能磁共振成像研究进展
- Author:
Sai TAN
1
,
2
;
Shijing HUANG
;
Jiliang FANG
Author Information
- Keywords: Vascular depression; diffusion tensor imaging; blood oxygenation level dependent-functional magnetic resonance imaging; research development
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(8):1346-1350
- CountryChina
- Language:Chinese
- Abstract: The paper was aimed to summarize the development of vascular depression (VD) in functional magnetic resonance imaging (fMRI) of brain research,including diffusion tensor imaging and blood oxygenation level dependentfMRI.Through the real-time imaging of brain tissues and brain function in VD patients,it was found that the neurological and brain function in the brain regions related to depression were changed.The main pathologic changes were abnormal white matter hyperintensities of the brains.The key link of VD pathogenesis was that limbic systemcortex-striatum-thalamus circuits were destroyed.And the main performance of VD in fMRI was abnormal brain function connection in prefrontal cortex,limbic cortex (i.e.,cingulate gyrus,hippocampal gyrus),amygdala,cerebellum,and etc.in fMRI.The pathogenesis of VD was complex.As a noninvasive living brain function detection technique,fMRI will play an important role in the comprehensive understanding of VD and provide new ideas in clinical diagnosis and treatment.