Research Development on Antidepressant and Anxiolytic Effects of Xiao-Yao Powder
10.11842/wst.2017.08.007
- VernacularTitle:逍遥散抗抑郁和抗焦虑研究进展
- Author:
Xiaojuan LI
1
;
Jiaxu CHEN
;
Xueming ZHOU
;
Tingye WANG
;
Ming SONG
;
Yajing HOU
;
Fangfang WANG
Author Information
1. 北京中医药大学中医学院 北京100029
- Keywords:
Xiao-Yao powder;
depression;
anxiety;
pharmacodynamic material basis
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(8):1300-1306
- CountryChina
- Language:Chinese
-
Abstract:
Depression and anxiety is one of common mental illness that are being seriously harm to the physical and mental health of human being in recent years.Depression and anxiety are difficult to be well treated with a single and targeted drug,owing to its biological-psychological-social interaction pathogenic feature.Due to its own multicomponent characteristics,traditional Chinese medicine (TCM) compound Xiao-Yao (XY) powder can exert the antidepression and anxiety effects from multi-level,multi-link and multi-target.Based on previous studies on effect and mechanism of XY powder on anti-depression and anxiety of our group,we proposed that XY powder had two main characteristics when treating depression and anxiety,which were "two-way adjustment" and "multi-target,multisystem,multi-level".Additionally,to further clarify the pharmacodynamic material basis of XY powder,more importance is that we should depend on the variety of disciplinary research methods,focused on the TCM syndrome and the combination of disease and TCM syndrome,brought both disease evaluation and syndrome evaluation method,took the importance of gut-brain axis (GBA),and combined with the correlation between the formula and the syndrome.
