Distribution of Pathogens in Primary Nephrotic Syndrome with Pulmonary Infection and Analysis of Traditional Chinese Medicine Syndrome
10.11842/wst.2017.07.020
- VernacularTitle:原发性肾病综合征合并肺部感染的病原菌分布及中医证候分析
- Author:
Yuan XU
1
;
Tonghuan LIU
;
Zhiren HE
;
Fuhua LU
;
Xusheng LIU
Author Information
1. 广东省中医院
- Keywords:
Primary nephrotic syndrome;
pulmonary infection;
pathogen;
traditional Chinese medicine syndrome
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(7):1209-1213
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to analyze the pathogen distribution,drug resistance and traditional Chinese medicine (TCM) syndrome of patients with primary nephrotic syndrome complicated with pulmonary infection for the guidance of clinical practice.The clinical data of 180 patients with primary nephrotic syndrome complicated with pulmonary infection were analyzed.The results showed that among 180 patients,117 were male,accounting for 65％;73.33％ of them were over 40 years old.Membranous nephropathy was the most common pathological type,accounting for 40％.Gram-negative bacteria were the main pathogen,accounting for 51.72％.The drug resistance rates of piperacillin/tazobactam,imipenem,amikacin,gentamicin were the lowest.The drug resistance rates of third generation of cephalosporins and quinolone antibiotics were in the middle.In TCM syndrome differentiation,central qi deficiency and phlegm syndrome occupied the highest proportion,accounting for 25.56％;and the phlegm heat in the lung syndrome,accounting for 17.78％;wind evil attacking the lung syndrome,accounting for 13.33％;qi deficiency and phlegm syndrome,accounting for 9.45％;qi deficiency,blood stasis and water stagnation syndrome,accounting for 8.89％;the mixture of deficiency and excess syndrome,accounting for 59.45％,with qi deficiency as the main part.It was concluded that middle-aged and older men,pathologic type of membranous nephropathy had the higher rate of suffering pulmonary infection.Gram-negative bacteria were the main pathogen.The choice of antibiotics should be based on piperacillin/tazobactam,and third generation of cephalosporins.Qi deficiency and phlegm syndrome was the most common TCM syndrome.
