Clinical Effect and Safety Study of Modified Qing-Fei-Jie-Du Decoction on Lobar Pneumonia in 60 Cases of Children
- VernacularTitle:清肺解毒汤加减治疗儿童大叶性肺炎60例临床疗效及安全性研究
- Author:
Guihua SONG
1
;
Zhiwei GUAN
;
Yan ZHANG
;
Weigang LV
;
Suping YU
;
Yanrong GUO
;
Wei ZHANG
;
Xuefeng WANG
Author Information
- Keywords: Qing-Fei Jie-Du decoction; children; lobar pneumonia; clinical effect; safety
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(6):1072-1075
- CountryChina
- Language:Chinese
- Abstract: This study was aimed to investigate the clinical effect and safety of Qing-Fei Jie-Du (QFJD) decoction on treating lobar pneumonia in children.Ninety cases of children diagnosed with lobar pneumonia in hospital were selected by double-centre,random and control method.Cases were divided into the test group (60 cases) and the control group (30 cases.The ratio between the test group and the control group was 2∶1.It can fully demonstrate the effect of the test group without any influence on the statistical analysis).Children of the control group were given conventional medicine with placebo,while children of the test group were given conventional medicine with modified QFJD decoction.The treatment course was 2 weeks.The clinical symptoms including fever,cough,lung rale,lung image (X-ray or CT scan),laboratorial index and safety were compared between two groups.The results showed that the recovery rate of the test group was 81.7％;and the recovery rate of the control group was 66.7％.The difference between them was statistically significant (P＜0.05).The comparison of safety between two groups indicated that the treatment of the test group was safer than control group with statistical difference (P＜0.05).It was concluded that modified QFJD decoction had a significant clinical effect and was very safe in the treatment of children with lobar pneumonia.
