Study on Chemical Constituents of Dioscorea opposita Thunb.

Weisheng Feng; Fang LI; Menghuan Guo; Yangang Cao; Wenjing Chen; Man QI; Yanyun Yang; Xiaolan Wang; Xiaoke Zheng

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Study on Chemical Constituents of Dioscorea opposita Thunb.

VernacularTitle:怀山药的化学成分研究
Author: Weisheng FENG ^{1
,

2} ; Fang LI ; Menghuan GUO ; Yangang CAO ; Wenjing CHEN ; Man QI ; Yanyun YANG ; Xiaolan WANG ; Xiaoke ZHENG
Author Information

1. 河南中医药大学药学院郑州450046
2. 呼吸疾病诊疗与新药研发河南省协同创新中心郑州450046
Keywords: Dioscorea opposita Thunb.; chemical constituents; extraction and isolation; structural identification
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(4):658-662
CountryChina
Language:Chinese
Abstract: This article was aimed to study the chemical constituents of Dioscorea opposita Thunb.The chemical constituents were isolated and purified by Diaion HP-20,Toyopearl HW-40,Sephadex LH-20,MCI Gel CHP-20,silica gel column chromatography and preparative HPLC,TLC,purification and isolation from Dioscorea opposita Thunb.The structures of isolated compounds were identified by thc physicochemical properties and spectral analysis.The result showed that 14 compounds were isolated from Dioscorea opposita Thunb.The chemical structures were elucidated as L-Tryptophane (1),Seguinosides F (2),1-methoxycarbonyl-β-carboline (3),Helichrysin A (4),Bungein A (5),Hydroquinone (6),Zarzissine (7),Cyclo-(Pro-Thr) (8),4-Hydroxy-3-methoxybenzyl alcohol (9),pyridine-3-carboxamide (10),Arbutin (11),Methyl syringate 4-O-β-D-glucopyranoside (12),L-Phenylalanine (13),1,2-benzenedicarboxylic acid,1,2-bis[2-(2-hydroxyethoxy) ethyl] ester (14).It was concluded that chemical compounds 1-14 were isolated for the first time from Dioscorea opposita Thunb.