Roles of Gut Microbiota on Occurrence and Development of Colorectal Cancer and Effects of Chinese Herbal Medicine Intervention
- VernacularTitle:肠道菌群对结直肠癌发生发展的作用及中药干预的影响
- Author:
Yanqin GU
1
;
Shibing SU
;
Ming ZHAO
Author Information
- Keywords: Chinese herbal medicine; colorectal cancer; gut microbiome; mechanism
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(4):590-595
- CountryChina
- Language:Chinese
- Abstract: Colorectal cancer (CRC) is one of the most common malignant tumors.Accumulating evidences suggests that gut microbiota play an important role in CRC initiation and progression.Chinese herbal medicine has certain regulation effects on disorders of gut microbiota.In current review,we discuss the changes of gut microbiota in CRC patients,and summarize the effects of gut microbiota on CRC progression and their underlying mechanisms through barrier function,inflammation,bacterial enzymes,toxic metabolites,as well as the effects of Chinese herbal medicine on gut microbiota.This review provides a basic scientific and clinical application of gut microbiota in CRC.
