Effect of Acupuncture on hs-CRP and IL-6 in Patients with Primary Hypertension Due to Excessive Retention of Dampness-heat
10.13460/j.issn.1005-0957.2017.11.1295
- VernacularTitle:针刺对痰湿壅盛型原发性高血压患者hs-CRP、IL-6的影响
- Author:
Mei-Fang LIU
1
;
Jing SHI
Author Information
1. 云南省中医医院
- Keywords:
Acupuncture therapy;
Hypertension;
Excessive retention of dampness-heat;
Inflammatory factors;
hs-CRP;
IL-6
- From:
Shanghai Journal of Acupuncture and Moxibustion
2017;36(11):1295-1298
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of acupuncture on the levels of hypersensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6) in patients with grade I primary hypertension due to excessive retention of dampness-heat,and discuss the relationship between inflammatory factors and the change of blood pressure.Method Sixty patients with grade I primary hypertension due to excessive retention of dampness-heat were randomized into a treatment group and a control group,30 cases each.The treatment group was intervened by acupuncture with points selected based on syndrome differentiation,and the control group was treated with acupuncture at non-meridian points,for 18 sessions in total.The 24-hour ambulatory blood pressure,and serum hs-CRP and IL-6 levels were compared before and after the treatment.Result After the treatment,the 24-hour systolic blood pressure (SBP) and diastolic blood pressure (DBP) were significantly changed in the treatment group (P＜ 0.01).There were significant differences in comparing the 24-hour SBP and DBP between the two groups after the treatment (P＜0.05).The serum hs-CRP and IL-6 levels dropped after the treatment in both groups but without statistical significances (P＞0.05).Conclusion Acupuncture is an effective approach in treating primary hypertension due to excessive retention of dampness-heat,and its action mechanism may be associated with the decrease of serum hs-CRP and IL-6 levels.
