Clinical analysis of factors affecting colorectal adenoma recurrence after endoscopic resection
10.3969/j.issn.1672-8467.2018.02.007
- VernacularTitle:影响结直肠腺瘤内镜摘除术后复发因素的临床分析
- Author:
Wen-Jing LIU
1
;
Xiao-Na HU
;
Da-Nian JI
;
Ren-Xiang HUANG
;
Zhi-Jun BAO
Author Information
1. 复旦大学附属华东医院消化科 上海 200040
- Keywords:
colorectal adenoma;
recurrence;
influencing factors;
Helicobacter pylori;
retrospective study
- From:
Fudan University Journal of Medical Sciences
2018;45(2):185-190
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the factors that might affect the recurrence after endoscopic resection of colorectal adenoma,we aim to provide a reference for the regular follow-up of colorectal adenoma after endoscopic resection.Methods In the Department of Gastroenterology,Huadong Hospital from Jan.,2013 to Dec.,2014,patients received endoscopic resection during hospital stay and postoperative follow-up colonoscopy.We collected their information of gender,age,smoking history,drinking history,hypertension,diabetes,fatty liver,cholecystectomy history,Helicobacter pylori (H.pylori) infection,related metabolic indicators,number of adenoma,size of adenoma,location of adenoma and pathology of adenoma.Multivariate and univariate analysis were performed by Logistic regression analysis to explore factors influencing the recurrence risk of colorectal adenoma.Results A total of 283 cases were enrolled.The recurrence rate of low-risk and high-risk adenoma was 39.3 ％ and 56.3 ％,respectively,and therate of all adenoma was 52.7％.Multivariate and univariate analysis both found that H.pylori infection (P＜0.001,OR:3.316 and 2.802,95％CI:1.869-5.884 and 1.660-4.728) and adenoma number (P＜0.001,OR:2.799 and 2.789,95％ CI:1.578-4.963 and 1.667-4.668) were risk factors for colorectal adenoma recurrence after endoscopic excision.Conclusions H.pylori infection and the number of base colorectal adenoma maybe associated with colorectal adenoma recurrence.
