The molecular features of aggressive papillary thyroid microcarcinoma
10.3760/cma.j.issn.1674-6090.2018.04.018
- VernacularTitle:侵袭性甲状腺乳头状微小癌的分子特征
- Author:
Jianlu SONG
1
;
Zhili YANG
Author Information
1. 200233,上海交通大学附属第六人民医院普通外科
- Keywords:
Papillary thyroid microcarcinoma;
Aggressiveness;
Molecular features
- From:
Chinese Journal of Endocrine Surgery
2018;12(4):339-341
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the incidence of papillary thyroid microcarcinoma (PTMC) increased significantly and the mortality did not change obviously,resulting in the confusion and dilemma of clinical treatment.The majority of scholars believe that aggressive PTMC requires immediate surgical intervention,but there are no accurate clinical or pathologic features to predict or assess the aggressiveness of PTMC.In this review,the molecular genetic characteristics of aggressive PTMC are summarized from three aspects:gene mutation,microRNA and single gene expression.