A comparative study on MRI appearance and pathological grading for pancreatic neuroendocrine tumors
10.3760/cma.j.issn.1674-6090.2017.06.012
- VernacularTitle:胰腺神经内分泌肿瘤的MRI表现与病理分级的对照研究
- Author:
Su SUN
1
;
Aichun YANG
;
Yuchuan FU
;
Zhihan YAN
;
Xiaojun ZHAO
Author Information
1. 浙江省温州医科大学附属第二医院放射科
- Keywords:
Pancreatic tumors;
Pathology;
Neuroendocrine neoplasms;
Magnetic resonance imaging
- From:
Chinese Journal of Endocrine Surgery
2017;11(6):490-493,499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of conventional and functional MRI image parameter in preoperative grade of pancreatic neuroendocrine tumours (pNET).Methods Data of 35 cases of pNET were retrospectively analyzed,including tumor size,intensity of T1WI's and T2WI's signal,enhancement feature,and apparent diffusion coefficients (ADC)value.All kinds of tumors were classified into G1 to G3 according to WHO's classification in 2010.Results There were 40 pNETs (mean size(4.2±2.9)cm) among the 35 patients (20 male,and 15 female).By WHO's tumor grading,the number of patients from G1 to G3 was 18(45％),12(30％),and 10(25 ％),respectively.A higher grade was associated with larger tumor size (P＜0.05).Intensity of T1WI and T2WI signal has no significance for predicting tumor grade.Enhancement feature had statistical significance on tumor's grade (P＜0.05).ADC value decreased with the increase of tumor's grade,(2.23±0.80) × 10-3,(1.80±0.73) × 10-3,(0.92±0.24) ×10-3 mm2/s respectively for tumors from grade G1 to G3.Conclusion Enhancement features of MRI image and ADC value are conducive to preoperative grading of pNET.
