Mild form disseminated photocoagulation treatment for moderate non-proliferative diabetic retinopathy
10.3980/j.issn.1672-5123.2018.7.36
- VernacularTitle:轻型播散性光凝治疗中度非增殖期糖尿病视网膜病变
- Author:
Xiu-Duo LIU
1
;
Qing LU
;
Hui-Di XU
;
Qian WANG
;
Jie ZHAO
Author Information
1. 200438,中国上海市杨浦区市东医院眼科
- Keywords:
retinal photocoagulation;
diabetic retinopathy;
visual field
- From:
International Eye Science
2018;18(7):1313-1316
- CountryChina
- Language:Chinese
-
Abstract:
·AIM:To observe the therapeutic effect of the mild form disseminated photocoagulation treatment for moderate non-proliferative diabetic retinopathy (MNPDR). ·METHODS: Prospective randomized controlled study. Totally 126 cases (209 eyes) with MNPDR were randomly assigned to two groups in ophthalmology department of Shanghai Shidong Hospital. There were 62 cases ( 103 eyes ) were treated with the mild form disseminated photocoagulation as the therapy group, 64 cases ( 106 eyes) were treated with control of blood glucose as the control group. All cases were followed up for 24mo. The best corrected visual acuity ( BCVA), fundus change and central visual field were observed and compared. · RESULTS: At 24mo after treatment, BCVA variety between two groups took on significant statistical difference which indicated that there were more eyes with improved or stable visual acuity in therapy group ( Hc=5. 942, P<0. 05). There was significant difference in fundus examination between two groups which indicated that there were more eyes with improved or stable fundus change in therapy group (Hc=12. 662, P<0. 05). There was no significant difference in average mean sensitivity (MS) between before and after laser therapy for 12mo (t=3. 1586, P>0. 05). During our follow-up, there were no complications likewise infection, hemorrhage, retinal membrane, injury of the macular fovear occurred. · CONCLUSION: The mild form disseminated photocoagulation therapy for moderate non-proliferative diabetic retinopathy is safe and effective without obvious complications, which can effectively delay the progression of diabetic retinopathy.
