Meta analysis of traditional Chinese medicine in the treatment of dry eye in recent years
10.3980/j.issn.1672-5123.2018.6.10
- VernacularTitle:中医药治疗干眼疗效的Meta分析
- Author:
Peng-Fei JIANG
1
;
Jun PENG
;
Ya-Sha ZHOU
;
Xiao-Fang PENG
;
Xiang LI
;
Yi-Chen LI
;
Qing-Hua PENG
;
Xiang-Dong CHEN
Author Information
1. 湖南中医药大学
- Keywords:
dry eye;
traditional Chinese medicine;
Meta analysis;
randomized controlled trials
- From:
International Eye Science
2018;18(6):1023-1027
- CountryChina
- Language:Chinese
-
Abstract:
· AIM:To evaluate the traditional Chinese medicine (TCM) for the treatment of dry eye effect in the past five years by using meta analysis method.· METHODS:According to the Cochrane evaluation system method,we searched Medline (January 2013 to October 2017),EMbase (2013-2017),Cochrane Library (2017),Wanfang database (2013-2017),VIP (2013-2017),and CNKI(2013-2017) for studies published.We included randomized controlled trials conducted the TCM in the treatment of dry eye.RevMan 5.0 statistical software data extraction and Meta analysis were conducted.· RESULTS:A total of 10 studies were identified,nine were from Chinese literature and one was from English literature,of which including 1 229 eyes.Nine of these studies performed BUT measurements at the end of the course of treatment.The results showed a statistically significant difference (P ＜ 0.00001).Nine studies performed tear flow measurements at the end of the course of treatment and the results showed a statistically significant difference (P ＜ 0.0001).Two studies performed FL measurements after the end of the course of treatment;the results showed no statistically significant difference (P=0.25).Three studies performed dry eye symptoms after the end of the course of treatment;the results showed that the differences were statistically significant (P=0.0003);the overall efficacy comparison,the difference between the two groups was statistically significant (P＜0.00001).· CONCLUSION:TCM treatment can significantly prolong BUT and increase tear flow,and has more advantages in the treatment of dry eye.
