Optical coherence tomography in diagnosis of early primary open angle glaucoma
10.3980/j.issn.1672-5123.2018.5.35
- VernacularTitle:光学相干断层扫描技术在原发性开角型青光眼早期诊断中的应用
- Author:
Ou HAI
1
;
Li GUO
;
Chun-Xia GUO
;
Zhi-Li CUI
Author Information
1. 中国人民解放军第四五一医院眼科
- Keywords:
optical coherence tomography;
primary open angle glaucoma;
retinal nerve fiber layer thickness;
optic disc parameters;
macular thickness
- From:
International Eye Science
2018;18(5):909-911
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To evaluate the clinical value of retinal nerve fiber layer (RNFL) thickness, optic disc parameters and macular thickness by optical coherence tomography (OCT) in early diagnosis of primary open angle glaucoma (POAG). METHODS: Sixty-five patients (eighty-five eyes) were selected as a study group and fifty-two normal people (seventy-eight eyes) were selected as a control group. The retinal nerve fiber layer thickness, optic disc parameters, including cup/disc(C/D) rate, cup area (CA), cup volume (CV), disc area (DA), rim area (RA) and rim volume(RV),and macular thickness were detected by Cirrus HD-OCT. The data were compared and analyzed. RESULTS: The retinal nerve fiber layer thickness of superior, inferior, temple, nasal and average in the study group were all significantly thinner than those of the control group (P<0.001). The cup area, cup volume and cup/disc ratio in the study group were significantly higher than those of the control group (P<0.001); while the rim area and rim volume in the study group were significantly lower than those of the control group (P<0 001). But the disc area was not significantly different between two groups(P>0.05). The macular thickness of superior, inferior, temple and nasal in the study group were all significantly thinner than those of the control group (P<0.001). CONCLUSION: OCT can detect the change of retinal nerve fiber layer thickness, optic disc parameters and macular thickness, it is helpful for early diagnosis of POAG.
