Serum Vitamin D level in Jordanian patients with exfoliation syndrome and exfoliative glaucoma
10.3980/j.issn.1672-5123.2018.5.03
- VernacularTitle:虹膜色素剥脱综合征和剥脱性青光眼中血清维生素D水平分析
- Author:
Shihadeh A WISAM
1
,
2
;
Al-Hashimi R MUSTAFA
;
Khalil B MOHAMMED
;
Al-Dabbagh ALAA
;
Al-Shalakhti MAJD
;
Jaradat A SAIED
;
Khader YOUSEF
Author Information
1. 22110 约旦,伊尔比德,约旦科技大学医学院
2. 21163约旦,伊尔比德,Yarmouk 大学医学院
- Keywords:
Vitamin D;
exfoliation syndrome;
exfoliative glaucoma
- From:
International Eye Science
2018;18(5):781-784
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To compare the level of serum Vitamin D in patients with exfoliation syndrome (XFS) and exfoliative glaucoma (XFG) with that in control subjects. METHODS: Serum levels of 25 - hydroxy Vitamin D ( Vitamin D ) were measured using liquid chromatography. Variables like age, sex and medical history of hypertension, diabetes mellitus and ischemic heart disease were reported. RESULTS:This study included a total of 55 patients with XFS/XFG and 60 control subjects. Patients with XFS/XFG were significantly older than control subjects (mean age:71.8y vs 67. 5y, P = 0. 002). Gender distribution was similar. The prevalence rates of diabetes, hypertension, and ischemic heart disease were not significantly different between the two groups. The mean of Vitamin D was 14.7 ng/mL for patients with XFS/XFG and 14. 9 ng/mL for control subjects with no significant difference. Although Vitamin D level was lower in the XFS/XFG group but multivariate analysis did not show significant difference in Vitamin D deficiency between the two groups after adjusting for age,gender,and medical conditions. CONCLUSION:The outcomes of our study are different from those in the literature. Vitamin D levels were low in both the XFS/XFG group and the control group being lower in the first one but that difference was not statistically significant. XFS and Vitamin D deficiency share common associations with certain systemic diseases. Further studies with larger numbers are needed to elaborate more on these associations and to support further the controversial literature.
