lncRNAs involved in the development and diseases of eyes
10.3980/j.issn.1672-5123.2018.3.11
- VernacularTitle:长链非编码RNA与眼的发育和疾病
- Author:
Li-Hua HU
1
;
Qi PU
;
Xin-Yu LI
Author Information
1. 华中科技大学同济医学院附属同济医院
- Keywords:
long non-coding RNAs;
eye development;
ocular diseases;
target gene
- From:
International Eye Science
2018;18(3):451-456
- CountryChina
- Language:Chinese
-
Abstract:
·Long non-coding RNAs (lncRNAs) refer to a kind of non-coding RNA which is longer than 200 nucleotides, with the characteristic of its numerous, diversity of types and modes of action. The biological functions of lncRNA involved in genomic imprinting, chromatin remodeling, translational control of mRNA, cell cycle and cell differentiation control, immune surveillance, constituting the skeleton of nuclear sub structure, etc. LncRNA plays an important role in individual development and human diseases. This paper mainly reviewed those lncRNAs that have been published, and closely related to eye development and diseases.
