Three Cases of Orbitofrontal Cholesterol Granuloma.
- Author:
Ju Hee CHANG
1
;
Sang Hyeok LEE
;
Wha Sun CHUNG
Author Information
1. Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea. shhlll@hanmail.net
- Publication Type:Case Report
- Keywords:
Cholesterol granuloma;
Orbitofrontal bone;
Proptosis
- MeSH:
Biopsy
- From:Journal of the Korean Ophthalmological Society
2005;46(7):1228-1234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report three cases of orbitofrontal cholesterol granuloma. METHODS: The study subjects were three patients with chief complaints of proptosis and upgaze limitation of ocular movement. Exophthalmometric values were 4~8 mm by Hertel exophthalmometer. Orbital CT and MRI scans were taken in all patients, and regarded as orbitofrontal cholesterol granuloma. In all cases, excisional biopsy was done through the lateral approach. RESULTS: Orbital CT scan showed an isodense to hypodense, well-defined, homogeneous mass and osteolytic lesion in the adjacent superolateral bony orbit. Orbital MRI scan showed a mass with high signal intensity in both T1- and T2-weighted images. Histopathologically, the specimen showed numerous slits like cholesterol clefts surrounded by multinucleated, foreign body type, giant cells with hemosiderin pigments. CONCLUSIONS: Orbitofrontal cholesterol granuloma, although rare, has typical clinical and radiologic features. Surgical excision has a high success rate without recurrence.
